PUBLICATIONS – wangLab

2024

Lai, Y.#, Zheng, W.#, Zheng, Y.#, Lu, H.#, Qu, S., Wang, L., … & Wang, S. (2024). Unveiling a novel entry gate: Insect foregut as an alternative infection route for fungal entomopathogens. The Innovation, 5(4). DOI: 10.1016/j.xinn.2024.100644 wsb27.pdf
Lai, Y., & Wang, S. (2024). Epigenetic Regulation in Insect–Microbe Interactions. Annual Review of Entomology, 70. https://doi.org/10.1146/annurev-ento-022724-010640 wsb28.pdf

2023

Jiang, Y.#, Gao, H.#, Wang, L., Hu, W., Wang, G., & Wang, S. (2023). Quorum sensing-activated phenylalanine metabolism drives OMV biogenesis to enhance mosquito commensal colonization resistance to Plasmodium. Cell Host & Microbe, 31(10), 1655-1667. https://doi.org/10.1016/j.chom.2023.08.017 wsb26.pdf
Gao, H.#, Jiang, Y.#, Wang, L.#, Wang, G., Hu, W., Dong, L., & Wang, S. (2023). Outer membrane vesicles from a mosquito commensal mediate targeted killing of Plasmodium parasites via the phosphatidylcholine scavenging pathway. Nature Communications, 14(1), 5157. https://doi.org/10.1038/s41467-023-40887-6 wsb25.pdf
Wang, L.#, Lai, Y.#, Chen, J., Cao, X., Zheng, W., Dong, L., … & Wang, S. (2023). The ASH1–PEX16 regulatory pathway controls peroxisome biogenesis for appressorium-mediated insect infection by a fungal pathogen. Proceedings of the National Academy of Sciences, 120(4), e2217145120. https://doi.org/10.1073/pnas.2217145120 wsb24.pdf
Ding, J.#, Cui, C.#, Wang, G.#, Wei, G., Bai, L., Li, Y., … & Wang, S. (2023). Engineered gut symbiotic bacterium-mediated RNAi for effective control of Anopheles mosquito larvae. Microbiology Spectrum, 11(4), e01666-23. https://doi.org/10.1128/spectrum.01666-23 wsb23.pdf
Wang SB* and Jacobs-Loren M*. (2023). Transgenesis and paratransgenesis for the control of malaria. In: Carballar-Lejarazú, R. (Ed.). (2023). Mosquito gene drives and the malaria eradication agenda (1st ed.). Jenny Stanford Publishing, Singapore, pp 21-29. Doi.org/10.1201/9781003308775

2022

Cui, C.#, Wang, Y.#, Li, Y., Sun, P., Jiang, J., Zhou, H., … & Wang, S. (2022). Expression of mosquito miRNAs in entomopathogenic fungus induces pathogen-mediated host RNA interference and increases fungal efficacy. Cell Reports, 41(4). https://doi.org/10.1016/j.celrep.2022.111527 wsb21.pdf
Wang, C., Xiao, D., Dun, B., Yin, M., Tsega, A. S., Xie, L., … & Xu, Y. (2022). Chemometrics and genome mining reveal an unprecedented family of sugar acid–containing fungal nonribosomal cyclodepsipeptides. Proceedings of the National Academy of Sciences, 119(32), e2123379119. https://doi.org/10.1073/pnas.2123379119 wsb20.pdf
Lai, Y., Wang, L., Zheng, W., & Wang, S. (2022). Regulatory roles of histone modifications in filamentous fungal pathogens. Journal of Fungi, 8(6), 565. https://doi.org/10.3390/jof8060565 wsb19.pdf

2021

Wang, G.#, Vega-Rodríguez, J.#, Diabate, A.#, Liu, J.#, Cui, C., Nignan, C., … Wang S.*(Lead Contact) & Jacobs-Lorena, M. (2021). Clock genes and environmental cues coordinate Anopheles pheromone synthesis, swarming, and mating. Science, 371(6527), 411-415. DOI: 10.1126/science.abd4359 wsb18.pdf
Gao, H.#, Bai, L.#, Jiang, Y., Huang, W., Wang, L., Li, S., … & Wang, S. (2021). A natural symbiotic bacterium drives mosquito refractoriness to Plasmodium infection via secretion of an antimalarial lipase. Nature microbiology, 6(6), 806-817. https://doi.org/10.1038/s41564-021-00899-8 wsb17.pdf
Wang, Y.#, Cui, C.#, Wang, G., Li, Y., & Wang, S. (2021). Insects defend against fungal infection by employing microRNAs to silence virulence-related genes. Proceedings of the National Academy of Sciences, 118(19), e2023802118. https://doi.org/10.1073/pnas.2023802118 wsb16.pdf

2020

Lai, Y., Cao, X., Chen, J., Wang, L., Wei, G.*, & Wang, S*. (2020). Coordinated regulation of infection-related morphogenesis by the KMT2-Cre1-Hyd4 regulatory pathway to facilitate fungal infection. Science Advances, 6(13), eaaz1659. DOI: 10.1126/sciadv.aaz1659 wsb15.pdf
Gao, H., Cui, C., Wang, L., Jacobs-Lorena, M.*, & Wang, S.* (2020). Mosquito microbiota and implications for disease control. Trends in parasitology, 36(2), 98-111. https://doi.org/10.1016/j.pt.2019.12.001 wsb14.pdf

2019

Cui, C., Wang, Y., Liu, J., Zhao, J., Sun, P., & Wang, S. (2019). A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection. Nature communications, 10(1), 4298. https://doi.org/10.1038/s41467-019-12323-1 wsb13.pdf
Bai, L., Wang, L., Vega-Rodríguez, J., Wang, G., & Wang, S. (2019). A gut symbiotic bacterium Serratia marcescens renders mosquito resistance to Plasmodium infection through activation of mosquito immune responses. Frontiers in microbiology, 10, 1580. https://doi.org/10.3389/fmicb.2019.01580 wsb10.pdf

2018

Qu, S., & Wang, S. (2018). Interaction of entomopathogenic fungi with the host immune system. Developmental & Comparative Immunology, 83, 96-103. https://doi.org/10.1016/j.dci.2018.01.010 wsb2.pdf

2017

Wang, S., Dos-Santos, A. L., Huang, W., Liu, K. C., Oshaghi, M. A., Wei, G., … & Jacobs-Lorena, M. (2017). Driving mosquito refractoriness to Plasmodium falciparum with engineered symbiotic bacteria. Science, 357(6358), 1399-1402. 10.1126/science.aan5478 wsb12.pdf
Wei, G., Lai, Y., Wang, G., Chen, H., Li, F., & Wang, S. (2017). Insect pathogenic fungus interacts with the gut microbiota to accelerate mosquito mortality. Proceedings of the National Academy of Sciences, 114(23), 5994-5999. https://doi.org/10.1073/pnas.1703546114 wsb11.pdf
Wang, C., & Wang, S. (2017). Insect pathogenic fungi: genomics, molecular interactions, and genetic improvements. Annual review of entomology, 62(1), 73-90. https://doi.org/10.1146/annurev-ento-031616-035509 wsb9.pdf
Lai, Y., Chen, H., Wei, G., Wang, G., Li, F., & Wang, S. (2017). In vivo gene expression profiling of the entomopathogenic fungus Beauveria bassiana elucidates its infection stratagems in Anopheles mosquito. Science China Life Sciences, 60, 839-851. https://doi.org/10.1007/s11427-017-9101-3 wsb3.pdf

2015

Wang, D., Li, S., Cheng, Z., Xiao, N., Cotter, C., Hwang, J….Wang, S. (2015). Transmission Risk from Imported Plasmodium vivax Malaria in the China–Myanmar Border Region. Emerging Infectious Diseases, 21(10), 1861-1864. https://doi.org/10.3201/eid2110.150679 wsb1.pdf

2014

Vega-Rodríguez, J., Ghosh, A. K., Kanzok, S. M., Dinglasan, R. R., Wang, S., Bongio, N. J., … & Jacobs-Lorena, M. (2014). Multiple pathways for Plasmodium ookinete invasion of the mosquito midgut. Proceedings of the National Academy of Sciences, 111(4), E492-E500. https://doi.org/10.1073/pnas.1315517111 wsb4.pdf

2013

Wang, S.*, & Jacobs-Lorena, M*. (2013). Genetic approaches to interfere with malaria transmission by vector mosquitoes. Trends in biotechnology, 31(3), 185-193. https://doi.org/10.1016/j.tibtech.2013.01.001 wsb8.pdf

2012

Wang, S., Ghosh, A. K., Bongio, N., Stebbings, K. A., Lampe, D. J., & Jacobs-Lorena, M. (2012). Fighting malaria with engineered symbiotic bacteria from vector mosquitoes. Proceedings of the National Academy of Sciences, 109(31), 12734-12739. https://doi.org/10.1073/pnas.1204158109 wsb7.pdf

2011

Wang, S., O’Brien, T. R., Pava-Ripoll, M., & St. Leger, R. J. (2011). Local adaptation of an introduced transgenic insect fungal pathogen due to new beneficial mutations. Proceedings of the National Academy of Sciences, 108(51), 20449-20454. https://doi.org/10.1073/pnas.1113824108 wsb6.pdf
Wang, S., Fang, W., Wang, C., & St. Leger, R. J. (2011). Insertion of an esterase gene into a specific locust pathogen (Metarhizium acridum) enables it to infect caterpillars. PLoS pathogens, 7(6), e1002097. https://doi.org/10.1371/journal.ppat.1002097 wsb5.pdf